Photobiomodulation Therapy for Chemotherapy-Induced Peripheral Neuropathy: Targeted Mechanisms and Optimized Strategies for Sensory Symptom Relief
Abstract
Chemotherapy-induced peripheral neuropathy (CIPN) is a widespread and often disabling effect of neurotoxic cancer therapies. Patients frequently experience sensory abnormalities such as numbness, tingling, heightened sensitivity to mechanical or cold stimuli (allodynia), and disrupted proprioception. These symptoms can persist long after treatment, significantly im-pairing daily function and quality of life. Photobiomodulation (PBM), which uses specific wavelengths of low-level red or near-infrared light, has recently emerged as a viable non-phar-macologic option for reducing these sensory disruptions.
